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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be9ee05edd4b0a757494b5e8bef3b70c8da0a1f91d78c152c40054bc1b58738' 
  AND token = '3qeDB4BFcEYcpHOkFGNTgQWJtXmcDrvU0wO69mgt2uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}