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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe453aa904fe46b7464f82baa0f1e4febd61bc65b4433733d98d52ebe60f448f' 
  AND token = 'aY6OZKsxoizaleoBqpyA4t9+XRkfALjGhcFt1SPR/O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}