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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0ce0499e84e96fbb6799fbe0c8184e69d5e946159ec80181bbdf93285b426c' 
  AND token = '5z1NYV8Y7fP93cmhPR9lClNBRvYnsJsuaQuAml6ZCq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}