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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be529e13a35be78b0ab62d96d381eece739061929b795c7035f5d84e7c5b155f' 
  AND token = 'M8SE0Y49yz2UelY6hIeSSBKG/Ze4UJ0OGjPJKtGlXf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}