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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a144f259e8d13e95da62ebf9024c999a48c2d509d1bf49ac09168fd754996fb6' 
  AND token = 'jzYT8OIjs2+2/V71y7RhzvTYsCaQdBsNhyEX7wsxgHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}