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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449d284f62ea3ea25b1169b4c2780429aa2581479b5da4da442f370eb16a4085' 
  AND token = '/IxiOkWGNE6C1rP1bCpx4B0YEVy2lfK7I2TRnXRmbkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}