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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e65782f28fc0cd9bdcf236bda0728e86a90002b9cefd141c035c0981a8c960f' 
  AND token = '2kSQ+HzcvKow4JEhhTCw1cQ0zxeTQSaIBHwfHY1pF48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}