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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178701da3b38ebf16620120e0c4f8d9d3f6a67d352b2c58f7b04e29471eb34a8' 
  AND token = 'tQUyNO38S0VP0WbtgpBsJLclZZmSQRpA6wzmC6BLPc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}