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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4ee9f21ac18689f4b7d89d527765fcbab6b464b7799e5a3e01cd427d2457153' 
  AND token = 'qL4ZA8TR6ltPt+bvlY1IgOlKz6l+9NkEYTnyKX0Mmpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}