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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae558600c5c1727c3373f9ce66c6b293c8fcc303c239a4439b38882da018181' 
  AND token = 'ZrlJUJw88V9KvU+9OsrqOkOokCnUTMPn9srhDNJXzkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}