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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70e4af5d3a44aba87024d991edbd84c4bf098dc85ce292b040707fcb0c7c6810' 
  AND token = '7Jsu4x2eXWzd/oWAO4WkmEttEhar5XZZxvUrZT49KG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}