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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a3b39fc420767237c1314d72853990af5e210c5a3350b50fb4c713acc1a3b6' 
  AND token = 'hMZozf4hxbTE4RqTSzDqVPPyfdO3DsGSeRDUXui07HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}