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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c58af385db700b23b0e4f9c434e3434d756185142ec4b6485680e908c68bd09d' 
  AND token = 'wrc+gerewtNMRi9DqdtN/uocBXvrSwTJ8M4EGZmtGW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}