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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d0c9292f05a36d8bf5ec388ab3856188eaec9e82f8dc0f7fbbffcc5da2f4f0' 
  AND token = '4Nwk3Ru68psNzys5xVbTDTeoSWEL4GjoltkRvMWTalE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}