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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22f3f0b434c4421315d6aeeae9a4c9e63e9547dced98504fb10c5fb33c31b9a' 
  AND token = '+smFSYGFqbUrrmexXaMivHkxuTkJ3ebecsgNSs/y3BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}