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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d548ea923d7cbe810ac79c445586956ced9d5a71e438b54b4e585e475e7b125' 
  AND token = 'ThDTulydArLZqna4LQTNrjy6FgxXZP5LmXye3jeSG8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}