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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15bcfe0b6c06a05d3cd569a950a35fdcd6a79d27aada4b066912505e51c3e9f4' 
  AND token = 'PuogSgxj5lY9SB5I4/p8q3rLhyFvZOvcsB0S86kIh/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}