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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24f3d618135ebd8fa65fe23fc15036d8451496dcddc5fc3f9dae3907fd80fe06' 
  AND token = 'JGloeSLyub6nqq1l9z5caTMkWCf4tTHz+JRiWufxhDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}