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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742291bc740eba4534e22e691ece046e6f24477cc10bc733a276ebb919f0f288' 
  AND token = 'Ergo7DyhaZQjC+0ysJITrTkZ+atRBeplBPc19iLq0s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}