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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2385932b0f64fd3b26c90f188a7f29b0772c8fa5ea65f3b5b555ffdee0a341' 
  AND token = 'Jc2/IjoNKYenZE6VgYD6sfJJXamSjCFrnOlSTQSGHSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}