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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1eb381e6449f6c11a9b816c54c58c5c618c5a2377fd6fa8717f05b066124185' 
  AND token = 'EUr0M+KyoIjqkPn+66GBWWpVx7WEdvAkTUpAEa4rAeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}