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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ed0c63128ad662935c8f69ed5f7ab5c9be94a0ffb377dd49848ed02c4fc417' 
  AND token = 'R+3lLYEEgLabFWM6ByPgnATWwon3WUPaFdiu1E+Mumo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}