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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f4c44fc5ddd8edadee531e881b1912f8a612044406d463d3b54c5a6e307cde' 
  AND token = '27/U4ZJqylH1fwhRSWmu/6Of+e2vrAP7TFZCqc6LUKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}