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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8faf9b75a63ba8e6d2596324bca3449a9a212637e15388913b2081b4dadea35' 
  AND token = 'lUqTf2NBaN8O9kcpZjmBiP+KwQA8crSrJICQYv7i2bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}