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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4133cf2d849c594227d14e5f8df021d454b5df943363fc6e3b5bcc37c4d0a6' 
  AND token = 'mjGaJ5R6DEajy9IBzYiquIvyeXV4IGoNTjUig54FVpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}