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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a683c764084184847c7b6c396cbcba5e951167e505d5cad4fddc92e3b441824' 
  AND token = 'Z3MA8Z6ALFm/IwmlrAp2A0oNwUfY2YWoTu6gbmFv18A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}