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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcce0643f344c89a21d14a4833cab86d3b06ceb37466599258c133da88dedefb' 
  AND token = '23I4aP3i0lwyu6Q1bl+nQVq+0UnrLCEzW8F8VMAc+QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}