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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff2b427c446784858c6f11a51e2f812704fa0d079b1500486fe3b0a136e6066' 
  AND token = 'kz0iKHQ0Y8+hc0R9iGjznDLeWc4nYeFACzs4TGmK1+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}