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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e296d2bcb89564b9b09d85a59d6ecd857926a7bba40313704935205235e6e7d4' 
  AND token = '+0aFbhhBlXqDy8Aefy5s8gS5Zz6NM+LVPxxFjt7ByOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}