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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff376e87498d9050748dfe1deae2530d887888b3e99a3114d9fdb3df1abde37' 
  AND token = 'Idsu2iOkiLRqZOBCH0xE8ddQPCj/J9nKyKC94g+JUp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}