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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e445e4df6e57ba96be7cc2abed70da4cae443e4d22555b9fcff89012cb444201' 
  AND token = '6PP6XmMhPwP9i7m4mOABzitnbxuV0LI6v2gVnObyEiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}