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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd3f1f408dc1afae1e7769e43da2963445e18a35ac3edca4b7649f3b5ecc6d71' 
  AND token = 'L3sm/uLKnPSDo1AwPwfGyfniiI5rBNLsd//2l7Yqk94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}