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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4b08a8153e9dbc064c79b62a56c2a6ed749806fc84dec4e8b15aaa5a5c75486' 
  AND token = 'zcjzM/vimt+9e56IJ3i9cgZYUySFbpJsyzJBQ0pcfmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}