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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e809a6e042c437456098d0fa64ad7e330fd96617106451be236363c421519672' 
  AND token = '/En91IaAzfKR4CbV3s57dobtpKKdOaTzJm7xD6im+XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}