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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0807e8c0081b4049c93ccb1dd6fe7803d46fd00a827e78fbf34e9fb3fc5312c' 
  AND token = 'mlD0k1M5sw51YmdbI6KeoADpWRX60L4XjHRlKLHAu+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}