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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dde81aeaa5e614295363c504567ff9377aaad7ab71272aa0b86ac3a21f374153' 
  AND token = 'JxvsLjbeIAOuF4mxT9WIr/kxbZr3uqMW4qV+BOUX1hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}