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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4001682b9e63d26350a430f6d78b0ab15db299f3aaaed7ba39ca1dadd963c6b7' 
  AND token = '4aoPdsc4azaEG4FKb0Wvu9Zqe9594YL6EhBlSN7mvfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}