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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1005048c389ab84a4a8e496c1347e81fe0ec8823e1f8abc9ca116d144ad4c287' 
  AND token = 'kA35wZ+A/Wzo8vffHRYicDe3FBsybcY/ERtgckW8s5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}