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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8dadf8025abfdc8f1ea949be487d4721023eee5a64d46f4f5fd1924ff580fdf' 
  AND token = 'N72Ic4bbySxBO/H4rAmWQkARcfrZmN3vv2CN1Iv2Kvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}