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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c88dc1d9b7a9f476dd03707b244c6a6b08c13f86b1a396ea73af5d4837c5bd2' 
  AND token = 'M5PTSYNTxIsL4Sd3+AaBtOLRmYkXPY2qN7OwmbBVrp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}