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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4006f56a64368daf74489ab0372499aaeecece46438ccd4b4843e00eb523e9f2' 
  AND token = 'RYP/JfrZw5Yj3NGiKA87Km68H8ZRuzfGcc8LC6KCnKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}