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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b05afd66b1e38dc434bdf9d4279898f0505275ce3da4e9d620fae5c3cea8500' 
  AND token = '3aW3uz/xpRySCbJucW0T/0vcJ/g//2GTR5Xbexhows4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}