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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9810a444dfe1b97762bef5f96ebe4874213fbde60bd780a3b7f21ad15f88c97' 
  AND token = '/GhJm0ir5oVOcxIZQmprbWBeln6xup4t8B2TmTTpVmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}