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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e876e2f14a578c26cc2db3d3662d568f216489ec11869703bec21336e7ece0' 
  AND token = 'xDZOgvNeLdPB4Uj55uDpy+OJLNfeLM53eXL5xj/bAhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}