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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec61aad4612e1369759de1f7022f849954af51ceff6bb5ce7c2e45118e0d106c' 
  AND token = 'k4CBoQMZJjtCefzOUwTACn4hZjNFLxqflUiVDp9UIFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}