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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71778c2da09b85fade3697d76c45ca1f548785fba9a95bceeb7c11333afa624c' 
  AND token = 'T/R4CPrVWQ8aWlIrXqv/jRueISoEj/+FcDpc4wwP5JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}