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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9a17c009345444c546dd03796e0885d710be2670cc6a1e617c8d30d921bfdf' 
  AND token = '/v1ecLJFQvXeRGJB3vlsvZAkw853fl+2FglUwSy5F8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}