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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0164644d8e700fe66a72fdf50c46c143a4fc91893bcd83fb185293d01603afc1' 
  AND token = 'OB9ClSBUVmA8spicFuCDuf7IalrCMXvkr2uVAyHjE98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}