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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1956aea9d418bd317e92dc8748e5f8d589cb85d135191e55df5f6088d6280393' 
  AND token = 'FOGNB3fheqJ00+TAL4Sq2w4ps2BRNVOUrGpjCmIy8IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}