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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048a43581a8425513da3788d51cb7033ff2d1c44aae57a89e714ac22eef3caa2' 
  AND token = 'iQFAGA3kGYp5OtWZkZ9lzvbOxiur7jP8N3TYtTH+Fek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}